Family : Labiatae

Plant Parts used :  Dried roots.

Chemical constituents :  Forskolin is the main active constituent.  Other minor constituents are de-acetyl forskolin, deoxy-forskolin and volatile oil.

Pharmacology : Forskolin – an active diterpenoid present in Coleus forskohlii root activates the enzyme adenylate cyclase which in turn initiates a myrid of critical events and processes within all the cells of the human body.  Adenylate cyclase and the chemicals activated by it are responsible for executing a various hormonal processes.  Forskolin induced stimulation may lead to blood vessel dilation, inhibition of allergic reactions and possibly an increased secretion of thyroid harmone. 

Therapeutic uses: Forskolin has been used in the treatment of congestive cardiomyopathy, glaucoma and bronchial asthma.  It is also used as anti-hypertensive, anti-thrombotic and broncho-spasmolytic.