Family : Caesalpiniaceae
Plant Parts used : Leaves & Pods
Chemical constituents : The main constituents in Senna leaves & Pods are Sennosides A & B. In addition, Sennosides C and D are also found in negligible amounts. Free anthraquinones including aloe-emodin, chrysophanol and rhein with their glycosides are also present.
Pharmacology : The sennosides and other anthroquinone derivatives possess a laxative effect. Sennosides and their natural metabolites specifically influence large intestinal motility. Acceleration of colonic transport seems to be a major component of the laxative action. Anthraquinone works by irritating the lining of the upper intestines which provokes reflex muscular activity in the colon resulting in a bowel motion.
Therapeutic uses : Senna is used as natural & time tested laxative in traditional as well as modern systems of medicine. Senna is a powerful cathartic used in the treatment of constipation, working through a stimulation of intestinal peristalsis. In combination with Cinnamon, Ginger, Fennel etc., it can be used for easing nausea, biliousness, halitosis etc..
Standardisation : Senna extract is standardized to 10%, 15%, 20% and 60% Calcium sennosides. |